Monday, December 1, 2014

CB-1 Receptors and Allosteric Regulation



I attended the last seminar of the semester that was presented by Dr. Debra Kendall.  I’m going to be honest, even with a bio major, her topic was very specific and very in depth and very hard to follow.  Many of the things she talked about about, and many of the terms she used were things I’ve never heard of at this point in my academic career.  What I did understand was that this research is important for medicinal purposes, because they are furthering our knowledge on how we can manipulate cells into behaving the way we need them to behave.  The GPCR they used was CB-1 which is a protein receptor that’s mostly found in the nervous system.  The reason they’re looking at using allosteric regulation as a new therapeutic method, is because it looks like it will be more efficient and effective than the previous method with orthosteric ligands.
General GPCR

CB-1

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