Natural Chiral Products
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Penicillin V contains three chiral centers that are circled in pink in the above photo. In reference to the stereo-chemistry that these chiral centers possess, number one is clockwise or "R," number two is also clockwise or "R," and finally number three is counterclockwise or "S" based on the level of priority that each center's multiple substituents have. |
Although penicillin can be used to treat strep throat, some people can be allergic to it. Even though it is a very powerful drug and often used in everyday practices, there are similar drugs that work in the same ways and can be substituted in cases where penicillin cant be used. These include amoxicillin (penicillin based) and cephalexin (non-penecillen based) which both work just as well for curing a bacterial infection (such as strep).
ReplyDeleteIts weird that you based you post on Penicillin and I based mine on Vancomycin, another tye of drug. They differ greatly in the number of chiral centers and the drug I researched in used if Penicillin isn't useful to a patient (if patient's body resists it)!
ReplyDeleteJessica,
ReplyDeleteI was particularly interested to see your post on Penicillin and read comments from both Brittany and Arial.
As someone that is dangerously allergic to Penicillin, I was interested to learn from the American College of Allergy, Asthma, and Immunology that up to 10% of the general patient population suffers from a penicillin related hypersensitivity (URL: http://www.acaai.org/allergist/allergies/Types/drug-allergy/Pages/penicillin-allergy.aspx).